This message indicates that the ORACLE_HOME environment variable is either set incorrectly in the registry or in the environment (Control Panel -> System -> Environment).
You could try removing the ORACLE_HOME environment variable from Control Panel -> System -> Environment. Alternatively, ensure that ORACLE_HOME is set to the correct destination in the registry (in HKEY_LOCAL_MACHINE\SOFTWARE\ORACLE\HOME<x> where <x> is the unique identifier of the ORACLE_HOME).
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